Enabling scalability by partitioning virtual environments using frontier sets

We present a class of partitioning scheme that we have called frontier sets. Frontier sets build on the notion of a potentially visible set (PVS). In a PVS, a world is subdivided into cells and for each cell all the other cells that can be seen are computed. In contrast, a frontier set considers pairs of cells, A and B. For each pair, it lists two sets of cells (two frontiers), FAB and FBA. By definition, from no cell in FAB is any cell in FBA visible and vice versa. Our initial use of frontier sets has been to enable scalability in distributed networking. This is possible because, for example, if at time t0 Player1 is in cell A and Player2 is in cell B, as long as they stay in their respective frontiers, they do not need to send update information to each other. In this paper we describe two strategies for building frontier sets. Both strategies are dynamic and compute frontiers only as necessary at runtime. The first is distance-based frontiers. This strategy requires precomputation of an enhanced potentially visible set. The second is greedy frontiers. This strategy is more expensive to compute at runtime, however it leads to larger and thus more efficient frontiers. Network simulations using code based on the Quake II engine show that frontiers have significant promise and may allow a new class of scalable peer-to-peer game infrastructures to emerge

Subjective Wellbeing, Health and Ageing

Life satisfaction dips around middle age and rises in older age in high-income, English-speaking countries, but that is not a universal pattern, according to a new report. In contrast, residents of other regions -- such as the former Soviet Union, Eastern Europe, Latin America and sub-Saharan Africa -- grow increasingly less satisfied as they age. The study -- conducted by researchers from Princeton University's Woodrow Wilson School of Public and International Affairs, Stony Brook University and University College London -- highlights how residents of different regions across the world experience varying life-satisfaction levels and emotions as they age

Combined Solar System and rotation curve constraints on MOND

The Modified Newtonian Dynamics (MOND) paradigm generically predicts that the external gravitational field in which a system is embedded can produce effects on its internal dynamics. In this communication, we first show that this External Field Effect can significantly improve some galactic rotation curves fits by decreasing the predicted velocities of the external part of the rotation curves. In modified gravity versions of MOND, this External Field Effect also appears in the Solar System and leads to a very good way to constrain the transition function of the theory. A combined analysis of the galactic rotation curves and Solar System constraints (provided by the Cassini spacecraft) rules out several classes of popular MOND transition functions, but leaves others viable. Moreover, we show that LISA Pathfinder will not be able to improve the current constraints on these still viable transition functions.Comment: 13 pages, 7 figures, accepted for publication in MNRA

A comparison of medetomidine and its active enantiomer dexmedetomidine when administered with ketamine in mice

Medetomidine-ketamine (MK) and dexmedetomidine-ketamine (DK) are widely used to provide general anaesthesia in laboratory animals, but have not been compared directly in many of these species, including rodents. This study aimed to compare the onset and depth of anaesthesia, and changes in vital signs, after intraperitoneal (IP) or subcutaneous (SC) administration of ketamine (75 mg kg-1) combined with medetomidine (1 mg kg-1) or dexmedetomidine (0.5 mg kg-1) using a randomised semi-crossover design with >= 48 hours between treatments in 10 male and 10 female mice. Each mouse was anaesthetised twice using the same administration route (IP or SC): once with each drug-ketamine combination. Anaesthetised mice were monitored on a heating pad without supplemental oxygen for 89 minutes; atipamezole was administered for reversal. The times that the righting reflex was lost post-injection and returned post-reversal were analysed using general linear models. Tail-pinch and pedal reflexes were examined using binomial generalized linear models. Pulse rate (PR), respiratory rate (fr), and arterial haemoglobin saturation (SpO2) were compared using generalized additive mixed models. There were no significant differences among treatments for the times taken for loss and return of the righting reflex, or response of the tail-pinch reflex. The pedal withdrawal reflex was abolished more frequently with MK than DK over time (P = 0.021). The response of PR and SpO2 were similar among treatments, but fr was significantly higher with MK than DK (P <= 0.0005). Markedly low SpO2 concentrations occurred within 5 minutes post-injection (83.8 +/- 6.7 %) in all treatment groups and were most severe after 89 minutes lapsed (66.7 +/- 7.5 %). No statistical differences were detected in regards to administration route (P <= 0.94). This study failed to demonstrate clinical advantages of the enantiomer dexmedetomidine over medetomidine when combined with ketamine to produce general anaesthesia in mice. At the doses administered, deep surgical anaesthesia was not consistently produced with either combination; therefore, anaesthetic depth must be assessed before performing surgical procedures. Supplemental oxygen should always be provided during anaesthesia to prevent hypoxaemia